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Fenofibrate 160 mg Fenofibrate 160 mg: Uses, Side Effects, Interactions... - WebMD
Fenofibrate 160 mg: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
Description: Fenofibrate belongs to a group of drugs known as "fibrates." It helps decrease triglycerides and increase "good" cholesterol (HDL) in the blood. High levels of triglycerides in the blood are associated with an increased risk of heart disease. Lowering triglyceride levels in people with high triglyceride blood levels may also decrease this risk.
How to use Fenofibrate 160 mg: Take this medication by mouth as directed by your doctor, usually once daily. Some brands may also be taken twice daily. Some tablets should be taken with food while others may be taken with or without food. Ask your pharmacist about your brand of fenofibrate. Dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your triglyceride levels will need to be tested frequently.
It is very important to continue taking this medication even if you feel well. Most people with high triglyceride and cholesterol levels do not feel sick.
Common side effects: • Muscle pain • Back pain • Increased risk of gallstones
Serious side effects (rarely): • Increased risk of pancreatitis (inflammation of the pancreas) • Liver damage • Muscle damage (rhabdomyolysis)
Allergies: Fenofibrate Before taking fenofibrate, tell your doctor or pharmacist if you are allergic to it; or to other "fibrates" (such as gemfibrozil); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Interactions: See also Warning section. Some products that may interact with this drug include: • "Blood thinners" (such as warfarin) • Bile acid-binding resins (such as colestipol, cholestyramine) • Colchicine • Gemfibrozil • HMG CoA reductase inhibitors (such as simvastatin, atorvastatin) • Other fibrates (such as bezafibrate, clofibrate)
Storage: Store at room temperature at 77°F (25°C); excursions permitted to 59°F to 86°F (15°C to 30°C). Keep all medicines away from children and pets.
Fenofibrate 160 mg Alternatives If you've tried fenofibrate and had issues with it, or if your doctor recommends trying something else, here are some alternatives:
Gemfibrozil: Works similarly to fenofibrate to lower triglycerides and increase HDL cholesterol. Available as generic.
Niacin: A B-complex vitamin also effective at lowering triglycerides while raising HDL. Available over-the-counter or by prescription.
Omega-3 fatty acid ethyl esters: A fish oil derivative that can help reduce triglycerides. Available by prescription.
Bile acid sequestrants: Medications like cholestyramine that work by removing bile acids from the gut. Can also lower LDL cholesterol.
Statins: While primarily used to lower LDL, some statins like atorvastatin also lower triglycerides.
Cholesteryl ester transfer protein (CETP) inhibitors: A newer class of medications that inhibit CETP, resulting in increased HDL. Evacetrapib is the most prominent.
Before taking fenofibrate or any alternative, discuss the pros, cons, and risks with your doctor. They will help you determine the best treatment for your specific situation.
Ordering Fenofibrate 160 mg Online It's possible to order fenofibrate online through pharmacies based outside the U.S. However, this is not recommended for several reasons: • The U.S. FDA provides oversight and regulation to ensure drugs sold in this country are safe and effective. Medications from foreign countries may not meet these standards. • Many websites claiming to sell fenofibrate online are actually pharmacies without a license. Their drugs may be counterfeit, contaminated, or contain dangerous ingredients. • U.S. customs may seize shipments of prescription drugs ordered online from overseas.
The safest way to obtain fenofibrate is through a local pharmacy or mail order service affiliated with a reputable U.S. pharmacy chain or insurance company. Always have a prescription from a doctor you have seen in person.
Some popular U.S. online pharmacies that require a valid prescription include: • Costco Pharmacy • CVS • Rite Aid Pharmacy • Walgreens • Express Scripts (mail order)
If you have trouble affording fenofibrate or other medications, talk to your doctor about patient assistance programs or coupons that can help reduce the cost.
Buying Fenofibrate 160 mg Without a Prescription It's important to never buy fenofibrate or any other prescription drug without a valid prescription from a doctor you have seen in person. Here's why: • Fenofibrate is a powerful medication that requires careful monitoring by a healthcare provider. They need to check your liver function with blood tests. • Taking fenofibrate incorrectly can lead to dangerous side effects like muscle damage and pancreatitis. Your doctor will need to regularly assess your response to the drug. • A doctor can help determine if fenofibrate is appropriate for your condition or if a different treatment is better suited to your needs. • Fenofibrate interacts with many other medications. Your doctor needs to review your drug list to ensure it's safe to add fenofibrate.
Neither a U.S. doctor nor a foreign doctor can legally issue a prescription for fenofibrate without an in-person exam first. Any online consult service claiming to be able to do so is likely a scam.
If you're having trouble affording fenofibrate or other medications, there are many legitimate patient assistance programs that can help. Non-profit organizations like NeedyMeds and the Partnership for Prescription Assistance offer resources. Your state health department may also have information.
What is Fenofibrate 160 mg? Fenofibrate 160 mg is a medication used to treat high levels of triglycerides in the blood. It belongs to a class of drugs called fibrates.
How does Fenofibrate work? Fenofibrate works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). This causes the liver to break down and eliminate more triglycerides. It also increases the production of high-density lipoprotein (HDL), the "good" cholesterol.
What are the side effects of Fenofibrate? Common side effects of fenofibrate include: • Increased risk of gallstones • Muscle pain and weakness • Back pain • Increased risk of pancreatitis (inflammation of the pancreas) • Stomach upset and abdominal pain
Rare but serious side effects can include: • Liver damage • Muscle damage (rhabdomyolysis) that can lead to kidney failure
Is Fenofibrate safe? Fenofibrate is generally safe when taken as directed by a doctor and under their supervision. However, it is not suitable for everyone. People with liver or gallbladder disease, pancreatitis, muscle disorders, or severe kidney disease should not take fenofibrate.
Fenofibrate can cause problems when taken with certain other medications, such as warfarin, cholestyramine, or statins. Your doctor will need to carefully assess your health and drug regimen before starting you on fenofibrate. They will also need to check your liver enzymes regularly with blood tests.
Can I take Fenofibrate if I have liver problems? Fenofibrate should not be used by people with active liver disease, liver enzyme elevations, or who have had a liver problem while taking a fibrate or statin in the past. However, the medication may still be appropriate for those with a history of liver problems if their doctor determines the potential benefits outweigh the risks.
Before starting fenofibrate, your doctor will check your liver enzymes with blood tests. They will also do regular liver enzyme tests while you are taking the drug to watch for signs of liver damage. If tests show a significant increase in liver enzymes, your doctor may need to reduce your dose of fenofibrate or switch you to a different medication.
Can I take Fenofibrate while pregnant or breastfeeding? Fenofibrate is category C for use during pregnancy, meaning it may be harmful to the fetus. It should only be taken during pregnancy if the potential benefit justifies the risk. There is no data on the safety of fenofibrate in breastfeeding, so it is not recommended for nursing mothers. Statins are likely a safer alternative for cholesterol management during this time.
What is the generic alternative to Fenofibrate? The generic alternative to fenofibrate is fenofibrate (brand names include Tricor, Lofibra, and Lipofen). The generic has the same active ingredients and is available at a lower cost. However, the brand names are available in different strengths and some have different inactive ingredients.
Your insurance coverage and cost may vary depending on whether you take the brand name or generic. Always check with your pharmacy or insurance company to see which is the better value for you.
How much does Fenofibrate cost? The cost of fenofibrate varies depending on the strength, brand name, and whether you pay cash or use insurance. Here are some approximate prices: • Tricor 160mg (brand): $150 per 30 tablets • Fenofibrate 160mg (generic): $40-$60 per 30 tablets • Lofibra 160mg (brand): $150-$200 per 30 tablets
Discount programs: • Manufacturer coupons: Tricor and Lofibra both have coupons that can reduce your copay to $15-$25 per month. • Cash discount programs: Services like Blink Health, GoodRx, and SingleCare offer discounted cash prices for fenofibrate at participating pharmacies.
Patient assistance programs: • The Tricor patient assistance program is available for uninsured and underinsured patients. You pay $30 per month. • Lofibra offers a patient assistance program for eligible patients. You pay $18 per month.
Check the drug manufacturer's website for the most up-to-date information on their programs.
Keep in mind that you may need to cover the full cost of fenofibrate until you reach your insurance deductible. Some discount programs and patient assistance plans may also have income and insurance requirements to be eligible. Always check the terms carefully.
Discount Fenofibrate Without Prescription Fenofibrate is a prescription-only drug in the United States. This means you cannot legally buy it without first seeing a doctor in-person and getting a valid prescription. Some ways to potentially get a discount on fenofibrate without a prescription include:
• Manufacturer Coupons: Some drug manufacturers offer coupons on their websites that can reduce your out-of-pocket cost for their brand name version of fenofibrate. However, these coupons typically require you to have a prescription and insurance.
• Discount Cards: Plans like Blink Health, GoodRx, and SingleCare are discount cards that can help you save money on fenofibrate when you pay cash instead of insurance. They may offer prices lower than some insurance plans.
• Cash Discount Programs: Some pharmacies offer cash discount programs that give you a set price for fenofibrate, usually lower than the insurance copay. Example programs include CVS Health's Prescription Savings Card and Walgreens Prescription Savings Club.
• Patient Assistance Programs: If you are underinsured or uninsured, some drug manufacturers and non-profit organizations offer patient assistance programs (PAPs) that can greatly reduce the cost of fenofibrate. You will need proof of income to qualify.
However, none of these options allow you to obtain fenofibrate without a prescription. It is illegal for any pharmacy or website to sell prescription drugs to U.S. consumers without a valid prescription written by a doctor they have seen in-person.
Buying fenofibrate or any medication from an unlicensed foreign pharmacy is dangerous. The drugs may be counterfeit, contain dangerous ingredients, or not meet U.S. quality standards. It's always best to work with your doctor and a reputable U.S. pharmacy to get your prescription for fenofibrate or any other controlled substance.
Fenofibrate 160 mg - Buy Without Prescription It's not legal in the U.S. to buy fenofibrate without a valid prescription from a doctor you have seen in-person. Fenofibrate is a controlled substance that requires close monitoring by a healthcare provider. They need to check your liver enzymes regularly with blood tests to watch for signs of liver damage.
Taking fenofibrate incorrectly or without supervision greatly increases your risk of dangerous side effects like muscle damage and pancreatitis. A doctor is essential to assess your starting triglyceride levels, overall health, and interaction risk with other medications before you begin treatment.
If you are having trouble affording fenofibrate, there are many legitimate resources available to help: • Manufacturer coupons and patient assistance programs can greatly reduce your out-of-pocket cost. • Discount cards like GoodRx and Blink Health can help you save money when paying cash. • Cash discount programs from pharmacies like CVS and Walgreens often have set prices lower than insurance copays. • Non-profit organizations like NeedyMeds and the Partnership for Prescription Assistance provide information on ways to get help paying for fenofibrate and other medications.
The best way to obtain fenofibrate safely is to work with your doctor and a reputable U.S. pharmacy. They will help you navigate the system to find the best price for your needs and budget. Always avoid buying controlled substances from foreign pharmacies or unlicensed websites. The drugs are often counterfeit and not meeting U.S. safety standards.
Fenofibrate 160 mg Brand Names Fenofibrate 160 mg is available under several brand names in the United States and worldwide. Some of the most well-known brands include:
Tricor (AbbVie): Available in the United States in strengths of 48 mg and 145 mg. Also available in 67 mg, 160 mg, and 200 mg in some foreign countries.
Lofibra (Teva Pharmaceuticals): Sold in the United States in 145 mg tablets. Available in 160 mg tablets in some other countries.
Antara (Lupin Pharmaceuticals): Sold in the United States in 43 mg and 130 mg capsules. Also available in 90 mg, 120 mg, and 160 mg in some foreign countries.
Fenoglide (Sciele Pharma): Sold in the United States in 40 mg and 120 mg tablets. Discontinued in some countries.
Lipidil (AbbVie): Sold in several countries outside the United States, including Canada, Australia, and some European nations. Available in 145 mg tablets.
Supralip (AbbVie): Sold in several Latin American countries, including Mexico and Chile. Available in 145 mg tablets.
All of these brands contain the same active ingredient, fenofibrate, but may have different inactive ingredients, strengths, or formulations (tablets vs. capsules). They work the same way to lower triglycerides and increase HDL cholesterol.
In the United States, the brand name fenofibrate products are available under various names depending on the manufacturer and dosage strength. However, the generic fenofibrate product is available across all manufacturers in multiple strengths.
Always talk to your doctor before switching brands of fenofibrate. They will ensure the change won't affect how well the medication works for you. Your insurance coverage may also vary by brand name, so check with your plan before filling your prescription.
Fenofibrate 160 mg - Safe to Take? Fenofibrate 160 mg is generally safe when taken as directed by a doctor and under their supervision. However, like all medications, it carries some risks of side effects that can range from mild to serious. Some of these risks include:
Common side effects: • Muscle pain and weakness (myalgia, myasthenia) • Muscle inflammation (myositis) • Increased risk of gallstones • Back pain • Stomach upset and abdominal pain • Increased risk of pancreatitis (inflammation of the pancreas)
Rare but serious side effects: • Liver damage • Muscle damage (rhabdomyolysis) that can lead to kidney failure • Severe allergic reactions
Your doctor will carefully weigh the benefits and risks of fenofibrate before prescribing it for you. They will regularly check your liver enzymes and assess you for muscle pain or inflammation. If you have any of the following, fenofibrate is not safe for you:
• Active liver disease or liver enzyme elevations • Severe kidney disease • Muscle disorders like muscular dystrophy • Pancreatitis or a history of pancreatitis • Gallbladder disease or a history of gallstones
Fenofibrate can also increase your risk of side effects when taken with certain other medications, such as:
• "Blood thinners" like warfarin • Bile acid resins like cholestyramine or colestipol • Gemfibrozil • Statins like atorvastatin or simvastatin • Colchicine
Always tell your doctor about all the medications you take, including supplements and over-the-counter drugs. They will assess the interaction risk and tell you if you need to adjust your regimen.
The most important thing you can do to take fenofibrate safely is to take it exactly as directed by your doctor. Always follow their instructions and go to your scheduled appointments for blood tests and check-ups. If you notice any side effects, even if mild, report them to your doctor right away. They may need to adjust your dose or switch you to a different medication.
Fenofibrate 160 mg - Best Prices Fenofibrate 160 mg is a commonly used medication for treating high triglycerides. The best prices for this drug can vary based on your insurance, location, and pharmacy. Here are some approximate prices to expect: • Tricor 160mg (brand): $150 per 30 tablets • Fenofibrate 160mg (generic): $40-$60 per 30 tablets • Lofibra 160mg (brand): $150-$200 per 30 tablets • Antara 160mg (brand): $100-$150 per 30 capsules • Fenoglide 160mg (brand): $50-$100 per 30 tablets (discontinued in some areas)
Ways to save money on fenofibrate 160mg:
Title: High Cholesterol and Triglycerides: The Deadly Duo
Introduction High cholesterol and elevated triglycerides in the blood are two closely related health concerns that can significantly increase the risk of heart disease and stroke when not managed properly. Cholesterol is a waxy, fat-like substance that is found in the blood and produced by the liver. It is essential for various bodily functions, but having too much of it in the bloodstream can lead to serious complications. Triglycerides, on the other hand, are a type of fat found in the blood and are a major source of energy for the body. Similar to cholesterol, having very high levels of triglycerides can pose a threat to cardiovascular health. In this article, we will delve into the dangers of high cholesterol and triglycerides, explore their causes and symptoms, and discuss the various treatment options available.
The Dangers of High Cholesterol Cholesterol plays a vital role in the body, but having excessively high levels of it can lead to serious health issues. Low-density lipoprotein (LDL) cholesterol, also known as "bad" cholesterol, can build up in the walls of the arteries, causing them to narrow and harden. This condition, known as atherosclerosis, can significantly increase the risk of heart attack and stroke. High cholesterol also raises the likelihood of developing peripheral artery disease, which occurs when the arteries in the legs, arms, stomach, or kidneys become narrowed or blocked.
High cholesterol is often referred to as a "silent killer" because it rarely shows any noticeable symptoms until a heart attack or stroke occurs. According to the Centers for Disease Control and Prevention (CDC), more than one-third of American adults have high cholesterol, and less than half of these individuals receive treatment. High cholesterol is a major concern, as it claims the lives of more than 600,000 Americans each year.
The Risks of High Triglycerides Triglycerides are an essential source of energy for the body and are primarily obtained from the foods we eat. However, very high levels of triglycerides can increase the risk of heart disease and pancreatitis, which is inflammation of the pancreas. Triglycerides are typically transported in the bloodstream by very-low-density lipoprotein (VLDL) and chylomicrons. High levels of these particles can increase the likelihood of atherosclerosis, which can lead to heart attack and stroke.
In rare cases, extremely elevated triglyceride levels (above 1,000 mg/dL) can cause acute pancreatitis. This is a painful and potentially life-threatening condition that requires immediate medical attention. High triglycerides may also contribute to the development of type 2 diabetes and kidney disease.
Causes of High Cholesterol and Triglycerides There are several factors that can contribute to high cholesterol and triglyceride levels. Some of the most common causes include:
High intake of saturated and trans fats: Consuming large amounts of saturated fats, found in animal products and full-fat dairy, and trans fats, commonly found in processed and fried foods, can significantly raise cholesterol levels. Genetics: A family history of high cholesterol or heart disease can increase an individual's risk of developing these conditions. Lack of physical activity: Regular exercise can help lower cholesterol and triglyceride levels by increasing the body's ability to use them for energy. Obesity: Being overweight or obese can raise cholesterol and triglyceride levels, as well as increase the risk of developing insulin resistance and type 2 diabetes. Smoking: Smoking damages the walls of the arteries, making them more susceptible to plaque buildup and increasing the risk of heart disease. Aging: Cholesterol levels tend to rise naturally with age, increasing the risk of heart disease over time.
Symptoms of High Cholesterol and Triglycerides High cholesterol and triglycerides rarely exhibit any noticeable symptoms until serious complications occur. However, there are some signs that may indicate high levels of these lipids:
Yellowish patches around the eyes or on the skin (xanthomas) Lumps in the tendons, particularly in the hands, knees, and feet (xanthomas) Fatty liver disease, which can cause abdominal pain, loss of appetite, and jaundice Blood tests: The only way to confirm high cholesterol and triglyceride levels is through a blood test. A lipid profile test measures the levels of total cholesterol, LDL cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides.
Treatment Options Fortunately, high cholesterol and triglycerides can often be managed through lifestyle changes and, if necessary, medication. Some of the most effective treatment options include:
Dietary Changes: Eating a heart-healthy diet can help lower cholesterol and triglyceride levels. This includes: Consuming high amounts of fruits, vegetables, and whole grains Choosing lean protein sources, such as poultry, fish, and plant-based options Limiting or avoiding saturated fats, trans fats, and added sugars Increasing consumption of omega-3 fatty acids, found in fatty fish, nuts, and seeds Physical Activity: Regular exercise can help raise HDL cholesterol levels and improve overall cardiovascular health. Aim for at least 150 minutes of moderate-intensity aerobic exercise per week. Weight Management: Maintaining a healthy weight can help lower cholesterol and triglyceride levels. Consult with a healthcare provider to determine an appropriate weight loss plan. Smoking Cessation: Quitting smoking can significantly reduce the risk of heart disease and stroke. Stress Management: Chronic stress can contribute to unhealthy habits that raise cholesterol and triglyceride levels. Engage in stress-reducing activities, such as meditation, yoga, or deep breathing exercises. Medications: If lifestyle changes are insufficient, medications may be prescribed to help lower cholesterol and triglyceride levels. Common medications include: Statins: These drugs work by blocking a substance in the liver that is needed to make cholesterol. Bile acid sequestrants: These medications work by binding with bile acids in the digestive tract and removing them from the body. This causes the liver to use more cholesterol to produce bile, which can help lower cholesterol levels. Fibrates: These drugs are primarily used to lower triglyceride levels. They work by increasing the breakdown of triglycerides and reducing the liver's production of VLDL. Niacin: This vitamin can help raise HDL cholesterol levels and lower LDL cholesterol and triglyceride levels. Omega-3 fatty acid supplements: These supplements, particularly those containing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to lower triglyceride levels.
Frequently Asked Questions
Q: What is a healthy level of cholesterol? A: A healthy level of total cholesterol is typically below 200 mg/dL. For LDL cholesterol, a level below 100 mg/dL is considered optimal. For HDL cholesterol, a level above 60 mg/dL is considered protective against heart disease. For triglycerides, a level below 150 mg/dL is considered normal.
Q: Can high cholesterol and triglycerides be prevented? A: Yes, high cholesterol and triglycerides can often be prevented or delayed by maintaining a healthy lifestyle, including a balanced diet, regular exercise, and not smoking.
Q: Are all types of cholesterol bad? A: No, HDL cholesterol is often referred to as "good" cholesterol because it helps remove excess cholesterol from the bloodstream and transport it to the liver for disposal.
Q: How often should I have my cholesterol levels checked? A: The American Heart Association recommends that adults 20 years and older have their cholesterol levels checked every 4-6 years. However, if you have a family history of high cholesterol or heart disease, your healthcare provider may recommend more frequent testing.
Conclusion High cholesterol and triglycerides are two interconnected health concerns that can significantly increase the risk of heart disease and stroke. While these conditions can be dangerous, they can often be managed through lifestyle changes and, if necessary, medication. By understanding the causes, symptoms, and treatment options of high cholesterol and triglycerides, individuals can take proactive steps to protect their cardiovascular health. Remember, it's essential to work closely with a healthcare provider to determine the best course of treatment for your specific needs.
Table 1: Desirable Blood Lipid Levels
| Lipid | Desirable Level |
|---|---|
| Total Cholesterol | Less than 200 mg/dL |
| LDL Cholesterol | Less than 100 mg/dL |
| HDL Cholesterol | 60 mg/dL or higher |
| Triglycerides | Less than 150 mg/dL |
Table 2: Foods to Eat and Avoid for Heart Health
| Food Group | Eat | Avoid |
|---|---|---|
| Fruits | A variety of fruits, including berries, citrus fruits, and stone fruits | Fruit juices, dried fruits, and fruits high in added sugars |
| Vegetables | Dark leafy greens, cruciferous vegetables, bell peppers, and carrots | Vegetables high in added salt |
| Protein | Lean meats (poultry, fish), legumes, nuts, and seeds | Processed meats, organ meats, and shellfish high in cholesterol |
| Dairy | Skim milk, low-fat yogurt, and fortified plant-based milk | Whole milk, cream, and high-fat cheese |
| Grains | Whole grains, such as brown rice, quinoa, and whole-grain bread | Refined grains, such as white rice and white bread |
| Fats | Avocado, nuts, seeds, and olive oil | Saturated fats (butter, lard), trans fats (partially hydrogenated oils), and coconut oil |
List 1: Lifestyle Changes for Lowering Cholesterol and Triglycerides
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