Intagra

Intagra 100 mg, 75 mg, 50 mg, 25 mg: What You Need to Know By Dr. Alistair Montgomery

Introduction Impotence is a common problem that affects millions of men around the world. While it was once believed to be a psychological issue, we now know that the vast majority of cases are caused by physical problems related to blood flow. Fortunately, there are now several effective treatments available, including Intagra. This article will review Intagra in detail, including its uses, side effects, dosages, and how to buy it.

What is Intagra? Intagra is the brand name for sildenafil citrate, a drug that increases blood flow to the penis. It does this by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a chemical that relaxes smooth muscle and allows increased blood flow. Intagra was the first oral PDE5 inhibitor approved by the FDA, and has been used by over 35 million men worldwide.

How Does Intagra Work? The process of erection involves the release of nitric oxide in the corpus cavernosum of the penis. This leads to an increase in cGMP, which causes relaxation of smooth muscle and an increase in blood flow to the penis. PDE5 breaks down cGMP, returning blood flow to normal and ending the erection. Intagra works by inhibiting PDE5, allowing an increase in cGMP and prolonged smooth muscle relaxation, increasing blood flow to the penis and allowing an erection to be maintained.

Uses of Intagra Intagra is primarily used to treat erectile dysfunction (ED) in men. It has also been approved to treat pulmonary arterial hypertension (PAH) under the brand name Revatio.

Erectile Dysfunction Intagra is the most commonly prescribed medication for ED. Studies have shown it to be effective in up to 80% of men with ED of all causes. The usual dose for ED is 25-100 mg taken 30 minutes to 1 hour before sexual activity. The dose should not be repeated within 24 hours.

Pulmonary Arterial Hypertension Intagra is used to treat PAH by relaxing the smooth muscle in the pulmonary arteries, reducing blood pressure and improving exercise tolerance. The usual dose for PAH is 20 mg three times a day.

Side Effects of Intagra Intagra is generally well-tolerated and safe. Common side effects, occurring in more than 2% of men, are:

• Headache (16%)
• Flushing (10%)
• Dyspepsia (7%)
• Nasal congestion (4%) Less common side effects include:
• Nausea and vomiting
• Dizziness and lightheadedness
• Increased sensitivity to light Rare but serious side effects include:
• Priapism (painful prolonged erection)
• Sudden vision loss
• Sudden hearing loss Men with pre-existing heart disease may be at increased risk for heart attack or death.

Side Effects Table

Contraindications and Interactions Intagra should not be used in:

• Men taking nitrates (e.g. nitroglycerin) for chest pain
• Men taking riociguat (Adempas) for PAH
• Men with severe heart or liver disease
• Men with low blood pressure
• Men with a recent history of stroke or heart attack

Intagra can interact with:

• Nitrates
• Riociguat
• Alpha-blockers (e.g. doxazosin for benign prostatic hyperplasia)
• Strong CYP3A4 inhibitors (e.g. ketoconazole, ritonavir)
• Moderate CYP3A4 inhibitors (e.g. erythromycin, clarithromycin)

Dosages of Intagra The usual starting dose for ED is 50 mg taken 30 minutes to 1 hour before sexual activity. The dose may be increased to 100 mg or decreased to 25 mg based on effectiveness and side effects. The dose should not be repeated within 24 hours.

For PAH, the usual dose is 20 mg three times a day.

Dosages Table

How to Buy Intagra Intagra is available by prescription only in the US. It can be purchased at a pharmacy or online from a reputable online pharmacy. The cost varies depending on the dose and quantity ordered.

Buying Options Table

Conclusion Intagra is an effective treatment for ED and PAH. Its ability to increase blood flow has made it a popular choice for millions of men worldwide. While generally safe, it does have some common and rare side effects. Used properly under a doctor's supervision, Intagra can help men regain their sexual function and quality of life. Consult with a doctor or healthcare professional before starting treatment with Intagra.